Anaesthesia and Intensive Care · 2000 · 24 citations · 11 references
Veterinary MedicineInfectious DiseasesMicrobiologyAntimicrobial PharmacotherapyMedical MicrobiologySepsisAntimicrobial TherapyBacterial InfectionsCommunity-acquired InfectionsHealthcare-associated InfectionsPulmonary InfectionsRespiratory Tract InfectionsCommunity-acquired Bacterial InfectionsCommunity-acquired Pneumonia TreatmentGroup A Streptococcal InfectionPneumonia Antibiotic TherapyPyogenic Bacterial InfectionStreptococcus SpeciesTherapy For Complicated PneumoniaToxic Shock Syndrome
We report a case of severe community-acquired pneumonia caused by Streptococcus pyogenes (Lancefield Group A streptoccocus) that was complicated by a streptococcal toxic shock syndrome. Although this micro-organism is an uncommon cause of community-acquired pneumonia, previously well individuals may be infected and the clinical course may be fulminant. A household contact was the likely point of infection. Invasive group A streptococcal disease continues to remain an important cause of morbidity and mortality in the community and therefore will continue to be encountered by intensive care physicians. Treatment of Group A streptococcal infection remains penicillin; however, clindamycin should be added in severe infection.
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Defining the Group A Streptococcal Toxic Shock Syndrome
Robert F. Breiman · JAMA · 1993 · 645 citations