Misclassification of Pulmonary Hypertension in Adults with Sickle Hemoglobinopathies Using Doppler Echocardiography

Abstract

In adults with SCD, a TRV of 2.5 m/s lacks specificity for use as a screening tool in the diagnosis of PH. Using a TRV of ≥ 2.88 m/s allows the TRV to be used as a screening tool and reduces the false-positive rate and need for unnecessary RHC.