Bulletin of the European Association of Fish Pathologists · 2001 · 109 citations · 11 references
Natural ResourcesInfectious DiseasesPathologyFish BiologyFish PathologyHistopathologyAnemiaAquatic Animal Infectious DiseasesFish Disease DiagnosisFish HealthFish HistopathologyFish NecropsyCytopathic EffectsFish DiagnosticsFish Disease PathogenesisInfectious Salmon AnemiaPathologic Gross FindingsPetechial HemorrhagesSpleen HistopathologyViral Cytopathic Effect
The first documented appearance of infectious salmon anaemia (ISA) at a US salmon farm is described. Fish presented clinically with listless behavior, exophthalmia, pale gills, and fin and skin haemorrhages. Gross necropsy findings included dark livers, swollen spleens and petechial haemorrhaging of mesenteric fat and internal organs. Laboratory testing results consisted of cytopathic effect attributable to ISAV on cell culture, appropriately amplified cDNA fragments by rt-PCR, and positive-range immunochemistry results. Histopathology suggestive of ISA was observed in kidney and liver sections.
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