The Medical Journal of Australia · 1989 · 64 citations · 17 references
MedicinePsychiatryPsychopharmacologySubstance Abuse ToxicologySubstance Use DisordersClinical Manifestations Of IntoxicationDrugs Of AbuseSubstance IntoxicationBarbiturate PoisoningDeliberate Self-injury
Over a 12-month period in 1985-1986, 325 cases of deliberate self-poisoning were admitted to the Princess Alexandra Hospital in Brisbane. This survey confirms that deliberate self-poisoning remains common, accounting for 19.6% of all admissions to the intensive-care unit, and 5.4% of all medical-ward admissions. In 232 (71.4%) cases formal psychiatric consultation occurred, and some form of follow-up was organized in 227 (69.8%) cases. In the total group, the female-to-male ratio was 1.5 to one. In the 325 cases, a total of 489 substances was consumed. Benzodiazepine agents were consumed the most often (39.5% of all substances), followed by antidepressant drugs (11.7% of substances) and paracetamol (7.2% of substances). Barbiturate drugs, which previously have been shown to be prominent in deliberate self-poisoning, accounted for only 1.6% of the substances that were used in this survey. Alcohol was consumed in almost one-third (31.1%) of cases. The diagnosis of adjustment disorder with depressed mood was the most-frequent primary diagnosis (64.8% of diagnosed cases), followed by personality disorder (16.7% of diagnosed cases), schizophrenia (5.5% of diagnosed cases) and major depression (3.7% of diagnosed cases). Nearly one-half (46.8%) of all cases involved a past history of deliberate self-poisoning. Comparison of the results of this survey with those of past surveys shows that the profile of deliberate self-poisoning is changing. Barbiturate usage has declined markedly with a reciprocal increase in benzodiazepine usage. A review of the prescribing pattern of antidepressant agents in groups of individuals who are at high risk of deliberate self-poisoning is suggested in the light of the frequency of this phenomenon.
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Neil Kessel · BMJ · 1965 · 190 citations · Full text
Self-poisoning with Drugs: A Worsening Situation
Anthony J. Smith · BMJ · 1972 · 111 citations · Full text
Changing pattern of drugs used for self-poisoning.
A. T. Proudfoot, J Park · BMJ · 1978 · 107 citations · Full text
A Treatment Outline for Depressive Disorders
Australian & New Zealand Journal of Psychiatry · 1983 · 102 citations
Trends in parasuicide and unemployment among men in Edinburgh, 1968-82.
Stephen Platt, Norman Kreitman · BMJ · 1984 · 102 citations · Full text