Structural organization of the rat gene for the arginine vasopressin-neurophysin precursor.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Chromatin, Dna Sequencing, Dna +15

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

Dna Sequencing, Nucleic Acid Chemistry, Dna +3

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

Jeffrey Vieira, Joachim Messing · Gene · 1982 · 6.1K citations

M13mp7-derived System, Dna Sequencing, Engineering +15

3′ Non-coding region sequences in eukaryotic messenger RNA

Nicholas Proudfoot, G.G. Brownlee · Nature · 1976 · 3K citations

Transcriptional Regulation, Natural Sciences, Rna Splicing +6

Why genes in pieces?

Walter Gilbert · Nature · 1978 · 2.3K citations · Full text

Genetics, Genomic Mechanism, Genetic Engineering +5