Liver injury induced by the Japanese herbal drug kamishoyosan.

Abstract

Traditional Japanese herbal medicines (kampo medicines) are currently used for various purposes, and they have even shown effectiveness in some cases that were resistant to conventional treatments. Most general practitioners in Japan consider kampo medicine to be safe and less harmful than many conventional medications. As described in this case report, however, kamishoyosan given to a 48-year-old woman for menopausal disturbance appeared to induce liver injury.