Reevaluation of prognostic factors in gastric leiomyosarcoma.

Abstract

The presence of distant metastasis and/or direct invasion, high mitotic rate, and severe nuclear atypia were confirmed to be unfavorable prognostic indicators. Mucosal ulceration, indicating high proliferative activity of the tumor, even if small, suggests a poor prognosis, although it was not significant in multivariate analysis.