PubMed · 1986 · 47 citations · 15 references
EngineeringAnatomyCartilage RepairRegenerative MedicineTissue EngineeringBone RegenerationBone Regeneration BiologyCartilage RegenerationEar AnatomyOrgan RegenerationOsteogenesisMammalian Tissue RegenerationTissue RegenerationVertebrate Appendage Regeneration
These studies, on a variety of laboratory, zoo and agricultural animals, show that the phenomenon of replacement of tissues lost in an ear punch is common to some other mammals as well as the rabbit, although the rabbit appears to be the most proficient in this process. It is suggested that the cartilage may be replaced in two ways, namely through the formation of a blastema as originally hypothesised by Markelova (Vorontsova & Liosner, 1960), and also from the perichondrium. The finding of bone tissue is supportive evidence enabling the suggestion that dedifferentiation, followed by deviant redifferentiation, does occur in the process of regeneration.
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Bone Cell Differentiation and Growth Factors
Marshall R. Urist, Robert J. DeLange, Gerald A. M. Finerman · Science · 1983 · 876 citations
Paul D. Benya, Silvia R. Padilla, Marcel E. Nimni · Biochemistry · 1977 · 317 citations