PubMed · 2013 · 25 citations · 40 references
AsthmaSleep DisordersBreathing DisordersNicotine AddictionSleep-related Breathing DisorderTobacco ControlSleep MedicineObstructive Sleep ApneaPublic HealthAtherosclerosisSleepTobacco UseSleep Disordered BreathingSleep DisorderCardiovascular DiseasePhysiologySleep ApneaTobacco SmokingMedicine
Obstructive sleep apnea (OSA), with an apnea/hypopnea index (AHI) > or =5 events per hour, is recognized as an important cause of medical morbidity and mortality, being associated with a wide range of significant medical consequences, including arterial hypertension, cardiovascular diseases, metabolic diseases, neurological diseases and psychological effects. Tobacco smoking is considered a predisposing factor for pulmonary and cardiovasculary diseases and a risk factor for developing OSA. Since snoring is frequent in smokers and a common symptom, even a preclinical form of OSA, it is reasonable to speculate that smoking is an independent risk factor for snoring and may be associated with OSA. Current studies have observed there is a synergistic effect between smoking and OSA, both increasing the risk of cardiovascular disease through oxidative stress, endothelial dysfunction and abnormal inflammatory response. OSA, itself could be responsible for nicotine addiction.
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The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults
Terry Young, Mari Palta, Jerome A. Dempsey et al. · New England Journal of Medicine · 1993 · 10.2K citations · Full text
José M. Marı́n, Santiago Carrizo, Eugenio Vicente et al. · The Lancet · 2005 · 4.6K citations