Iatrogenic opiate addiction: successful detoxification with clonidine

The Pharmacological Basis of Therapeutics.

Annals of Internal Medicine · 1971 · 885 citations

Molecular Pharmacology, Pharmacological Study, Pharmacodynamics +6

Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine

George K. Aghajanian · Nature · 1978 · 799 citations

Behavioral Neuroscience, Neuroanatomy, Medicine +14

CLONIDINE BLOCKS ACUTE OPIATE-WITHDRAWAL SYMPTOMS

MarkS. Gold, D. Eugene Redmond, H D Kleber · The Lancet · 1978 · 707 citations

Addiction, Medicine, Neuropharmacology +6

Opiate Withdrawal Using Clonidine

Mark S. Gold · JAMA · 1980 · 320 citations

Substance Abuse, Psychoactive Drug, Clonidine Hydrochloride +14

A comparison of clonidine with morphine for antinociceptive and antiwithdrawal actions.

Sharmonay Fielding, Jeffrey C. Wilker, Mary Hynes et al. · Journal of Pharmacology and Experimental Therapeutics · 1978 · 225 citations