Anaesthesia and Intensive Care · 2004 · 28 citations · 10 references
MedicinePharmacotherapySurgeryAnesthesiaIntravenous SedationPediatric PharmacotherapyPediatric AnesthesiaPediatric SedationProcedural SedationSedation ProtocolsSedation TechniquesSedative PharmacologyAgonist ActivityAnalgesia For Procedural SedationDexmedetomidine AnalgesiaDexmedetomidine PharmacologySedation For Pediatric PatientsSedation For Radiation TherapySedative PotencyStereotactic Ablation
Dexmedetomidine is a potent alpha2 adrenergic agonist, with sedative and analgesic properties which may make it a suitable sedative agent for procedures on paediatric patients. A six-year-old boy required sedation for stereotactic radiosurgical ablation of an arteriovenous malformation on two occasions. Sedation with dexmedetomidine was planned, with increased dosage used on the second occasion. On both occasions dexmedetomidine was inadequate as a sole agent and required supplementation with other agents.
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Controlled Sedation with Alphaxalone-Alphadolone
Michael A. E. Ramsay, T.M. Savege, B. R. Simpson et al. · BMJ · 1974 · 2.9K citations · Full text
Sedative, Amnestic, and Analgesic Properties of Small-Dose Dexmedetomidine Infusions
Judith Hall, Toni D. Uhrich, Jill A. Barney et al. · Anesthesia & Analgesia · 2000 · 1.1K citations
European Journal Of Haematology · 2015 · 791 citations