Choroidal Nonperfusion with Significant Subretinal Exudation after PDT of Predominantly Classic CNV: An OCT and FFA Study

Abstract

PURPOSE: Despite the increasing use of antivascular endothelial growth factors (anti-VEGF), photodynamic therapy (PDT) with Verteporfin is still considered the gold standard treatment of subfoveal and juxtafoveal classic choroidal neovascularization (CNV). METHODS: Case report. RESULTS: The authors report a case of a 72-year-old man who developed choroidal nonperfusion and significant subretinal fluid formation with associated severe visual loss following PDT of predominantly classic juxtafoveal CNV. CONCLUSIONS: Although reported separately, these two complications have not been previously reported to occur in association after PDT treatment of classic CNV and may represent exaggeration of normal events occurring after PDT.