Concepedia

Study of Nucleophile Binding in the Penicillin Acylase Active Center. Kinetic Analysis

Maxim I. Youshko, Alexander L. Bukhanov, Vytas K. Švedas

Biochemistry (Moscow) · 2003 · 10 citations · 8 references

DOI

Concepts

References

8

Mechanism and yields in enzyme catalysed equilibrium and kinetically controlled synthesis of β-lactam antibiotics, peptides and other condensation products

Volker Kasche · Enzyme and Microbial Technology · 1986 · 367 citations

, , +12

Penicillin Acylase in the Industrial Production of β-Lactam Antibiotics

Alle Bruggink, Eric C. Roos, Erik de Vroom · Organic Process Research & Development · 1998 · 315 citations

, , +15

Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism 1 1Edited by K. Nagai

Colin E. McVey, Martin Walsh, Guy Dodson et al. · Journal of Molecular Biology · 2001 · 157 citations

, , +12

Characterization of the β-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies

Wynand Alkema, Charles M. H. Hensgens, E.H. Kroezinga et al. · Protein Engineering Design and Selection · 2000 · 80 citations · Full text

, , +17

Kinetics and mechanism of acyl transfer by penicillin acylases

Jan Konečný, A. Schneider, M. Sieber · Biotechnology and Bioengineering · 1983 · 30 citations

, , +17