PubMed · 2006 · 22 citations · 0 references
MedicineNeurologyOphthalmologyCranial Nerve DisordersDiabetologyNeuro-ophthalmologyCranial Nerve PalsiesDiabetes MellitusDiabetic Foot DiseaseDiabetic NeuropathyNeuro-ophthalmic DisordersCavernous Sinus InvolvementDiabetic Cranial NeuropathyIsolated Cranial Nerve PalsyMultiple Cranial Nerve PalsiesOcular Manifestations Of DiabetesPainful OphthalmoplegiaPainful PolyneuropathyTolosa-hunt Syndrome
Although isolated cranial nerve palsies are common in patients with diabetes mellitus, multiple simultaneous cranial neuropathies are rare. We report a 48-year-old man, a known case of diabetes mellitus, who presented with facial palsy, foot drop and painful ophthalmoplegia of the left eye. The initial differential diagnosis included diabetic polyneuropathy, septic cavernous sinus thrombosis, mucormycosis and the Tolosa Hunt syndrome. Magnetic resonance (MR) imaging findings were consistent with those of the Tolosa Hunt syndrome. The patient had a remarkable complete resolution of his ophthalmoplegia after four weeks of steroid treatment, with repeat MR imaging showing resolution of the initial changes.