PubMed · 2004 · 112 citations · 0 references
PharmacyPharmacokineticsPharmacologyBioavailabilityDrug DeliveryPulmonary Drug DeliveryAntimicrobial Penetration Into TissuesPharmacokinetics Of AntimicrobialsPulmonary PharmacokineticsVeterinary Antimicrobial TherapyAntimicrobial Drug DeliveryAntimicrobial Use In CattleMycoplasmal PneumoniaMycoplasmal Respiratory DiseasePharmacokinetics Of Veterinary AntimicrobialsRespiratory Bacterial Infections TreatmentVeterinary Antibiotic TherapyVeterinary Pharmacokinetics
The pharmacokinetics of the new triamilide antibiotic tulathromycin was investigated in two cattle studies. Following a single subcutaneous injection, the drug was rapidly absorbed and bioavailability was excellent. High and persistent levels of the drug in lung tissue were observed as well. These attributes are advantageous for an antimicrobial drug indicated for the treatment of bacterial and mycoplasmal respiratory diseases in cattle.