TEN YEARS' EXPERIENCE WITH THOROTRAST HEPATOSPLENOGRAPHY

Abstract

Article1 March 1943TEN YEARS' EXPERIENCE WITH THOROTRAST HEPATOSPLENOGRAPHYWALLACE M. YATER, M.D., F.A.C.P., FRED O. COE, M.D.WALLACE M. YATER, M.D., F.A.C.P.Search for more papers by this author, FRED O. COE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-18-3-350 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlmost 11 years ago we began to employ thorium dioxide sol intravenously for the purpose of demonstrating radiographically the liver and spleen as first used by Radt1, 2, 3, 4 and Oka.5, 6 Since that time we have used this method of diagnosis in more than 300 patients. This figure does not include the many cases of arterial and venous disease in which we have used smaller amounts of thorotrast‡ for angiography.In 1933 Yater and Otell7published a report of our clinical experience with 100 patients, and in 1936 Yater, Otell and Hussey8reported a follow-up study of 200...Bibliography1. RADT P: Eine Methode zur röntgenologischen Kontrastdarstellung von Milz und Leber, Klin. Wchnschr., 1929, viii, 2128-2129. CrossrefGoogle Scholar2. RADT P: Über die körnige Ablagerung colloider Farbstoffe in den Leberparenchymzellen von Kanninchen nach intravitaler Injektion (nach Versuchen mit Tusche und Eisen), Ztschr. f. d. ges. exper. Med., 1930, lxix, 721-741. CrossrefGoogle Scholar3. RADT P: Zur röntgenologischen Kontrastdarstellung von Leber und Milz, Verhandl. d. deutsch. Gesellsch. f. inn. Med., Kong., 1931, xliii, 443-451. Google Scholar4. RADT P: Eine Methode zur röntgenologischen Sichtbarmachung von Leber und Milz durch Injektion eines Kontrastmittels (Hepato-Lienographie), Med. Klin., 1930, xxvi, 1888-1891. Google Scholar5. OKA M: Eine neue Methode zur röntgenologischen Darstellung der Milz (Lienographie), Fortschr. a. d. Geb. d. Röntgenstrahlen, 1929, xl, 497-501. Google Scholar6. OKA M: Klinische Anwendung der "Lienographie" einer neuen Methode zur röntgenologischen Darstellung von Milz und Leber, Fortschr. a. d. Geb. d. Röntgenstrahlen, 1930, xl, 892-898. Google Scholar7. YATEROTELL WMLS: Hepatosplenography with thorium dioxide sol: clinical experience with one hundred patients, Jr. Am. Med. Assoc., 1933, cl, 507-514. CrossrefGoogle Scholar8. YATEROTELLHUSSEY WMLSHH: Hepatosplenography with stabilized thorium dioxide sol: a follow-up study of 200 patients examined over a period of five years, Radiology, 1936, xxvii, 391-409. CrossrefGoogle Scholar9. ORRPOPOFFROSEDALESTEPHENSON CRGDRSBR: A study of the effect of thorium dioxide sol injected in rabbits, Radiology, 1938, xxx, 370-381. CrossrefGoogle Scholar10. TAFT RB: The radio-activity of thorium dioxide sol, Jr. Am. Med. Assoc., 1937, cviii, 1779-1781. CrossrefGoogle Scholar11. Report of Council on Pharmacy and Chemistry: Thorotrast, Jr. Am. Med. Assoc., 1932, xcix, 2183-2185. Google Scholar12. MARTLAND HS: The occurrence of malignancy in radioactive persons, Am. Jr. Cancer, 1931, xv, 2435-2516. Google Scholar13. SELBIE FR: Tumors in rats and mice following the injection of thorotrast, Brit. Jr. Exper. Path., 1938, xix, 100-107. Google Scholar14. FOULDS L: The production of transplantable carcinoma and sarcoma in guinea pigs by injections of thorotrast, Am. Jr. Cancer, 1939, xxxv, 363-373. Google Scholar15. STENSTROM W: Elimination of radioactive elements of patients and rabbits after injection of thorotrast, Radiology, 1941, xxxvll, 698-704. CrossrefGoogle Scholar16. RIGLERKOUCHYABRAHAM LGRAL: The effects of thorium dioxide sol (thorotrast) on the human liver, Radiology, 1935, xxv, 521-532. CrossrefGoogle Scholar17. REEVES RJ: The use of thorium dioxide in the roentgenographic study of liver abscess, Am. Jr. Roentgenol., 1936, xxxvi, 923-927. Google Scholar18. KOSTER H: Thorium dioxide as an aid in the differential diagnosis of pylephlebitis, Radiology, 1940, xxxv, 728-734. CrossrefGoogle Scholar19. YATERWHITMORE WMER: Histopathologic study of tissues of 65 patients injected with thorium dioxide sol for hepatosplenography, Am. Jr. Med. Sci., 1938, cixv, 198-205. CrossrefGoogle Scholar20. YATER WM: Rate of deposition of thorotrast in the human liver and spleen, Am. Jr. Roentgenol., 1937, xxxviii, 447-449. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.*Read at the St. Paul meeting of the American College of Physicians, April 24, 1942.From the Departments of Medicine and Radiology of the Georgetown University and Gallinger Municipal Hospitals, Washington, D. C.†From the Radiological Clinic of Drs. Groover, Christie and Merritt.‡Thorotrast is the trade name given by the Heyden Chemical Company to its stabilized colloidal solution of thorium dioxide, which contains 25 per cent by volume of thorium dioxide. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInvestigation and treatment of arterial disturbances in the lower limbsOsteosarcoma associated with thorotrast administration. Report of two cases and literature reviewRöntgendiagnostik der MilzLate clinical and roentgen observations following thorotrast administrationSpätschäden nach ThorotrastanwendungHepatographyRADIOLOGICAL DEMONSTRATION OF LIVER METASTASES USING THORIUM DIOXIDE (“THOROTRAST”)Thorotrast retention following angiography: A case with post-mortem studiesPrimary Liver Cell Carcinoma 24 Years after Intravenous Injection of ThorotrastAplastic anemia fourteen years following administration of thorotrastDoppelcarcinom nach Thorotrast-ArteriographieLATE CLINICAL CHANGES FOLLOWING THE INTERNAL DEPOSITION OF RADIOACTIVE MATERIALS*WILLIAM B. LOONEY, M.D.The Differential Diagnosis of Hepatomegaly and SplenomegalyPyogenic solitary liver abscessLIVER AND SPLEEN VISUALIZATION BY A SIMPLE ROENTGEN CONTRAST METHOD*SAMUEL ZELMAN, M.D., F.A.C.P.Pylephlebitis and pyogenic liver abscess 1 March 1943Volume 18, Issue 3Page: 350-366KeywordsAngiographyDiagnostic radiologyGratitudeHospital medicineLiverSpleen ePublished: 1 December 2008 Issue Published: 1 March 1943 PDF downloadLoading ...