Concepedia

Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma–hemorrhage

Ryan Stapley, Cilina Rodriguez, Joo‐Yeun Oh, Jaideep Honavar, Angela Brandon, Brant M. Wagener, Marisa B. Marques, Jordan A. Weinberg, Jeffrey D. Kerby, Jean‐François Pittet,

Free Radical Biology and Medicine · 2015 · 54 citations · 43 references

DOI

Concepts

References

43

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

John D. Belcher, Chunsheng Chen, Julia Nguyen et al. · Blood · 2013 · 689 citations · Full text

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Evolution of adverse changes in stored RBCs

Elliott Bennett‐Guerrero, Tim H. Veldman, Allan Doctor et al. · Proceedings of the National Academy of Sciences · 2007 · 623 citations · Full text

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Nitric Oxide Scavenging by Red Blood Cell Microparticles and Cell-Free Hemoglobin as a Mechanism for the Red Cell Storage Lesion

Chenell Donadee, Nicolaas J.H. Raat, Tamir Kanias et al. · Circulation · 2011 · 564 citations · Full text

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Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation

Jack H. Crawford · Blood · 2005 · 495 citations · Full text

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A Central Role for Free Heme in the Pathogenesis of Severe Sepsis

Rasmus Larsen, Raffaella Gozzelino, Viktória Jeney et al. · Science Translational Medicine · 2010 · 488 citations · Full text

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