Neuroblastoma : tumor biology and therapy

Abstract

Preface. Introduction. PART I: TUMOR BIOLOGY AND HISTOLOGY. Molecular Biology. Immunology and Targeted Immunotherapy of Neuroblastoma. Patterns of Catecholamine Metabolism in Neuroblastoma. Biochemical Monitoring in Neuroblastoma with Serum Ferritin and GD2 Ganglioside. Histiogenesis and Histopathology of Neuroblastoma. PART II: CLINICAL MANAGEMENT. Radiographic Imaging in Neuroblastoma. Radioiodinated MIBG in Management of Neuroblastoma. Clinical Staging. Neuroblastoma of Infancy. Neuroblastomas of the Head and Neck. Neuroblastomas of the Neck and Chest. Surgical Management of Neuroblastoma. Radiotherapy for Neuroblastoma. Chemotherapy for Neuroblastoma. Use of Bone Marrow Purging and Autologous Bone Marrow Transplantation. PART III: PROGNOSIS AND FUTURE PERSPECTIVES. Early Diagnosis by Urinary Screening for Catacholamines in Japan. Urinary Catacholamine Screening in the USA. Prognosis: Biological Vagaries in Neuroblastoma. Perspective for Future Research.