Leukemic meningitis in B-cell chronic lymphocytic leukemia: resolution following intrathecal methotrexate

Abstract

Unlike in other lymphoproliferative diseases such as acute lymphocytic leukemia (ALL) and non-Hodgkin malignant lymphomas, central nervous system (CNS) and leptomeningeal involvement are extremely rare in chronic lymphocytic leukemia (CLL), so much so that no mention of this complication is to be