PubMed · 1989 · 115 citations · 0 references
Life SciencesOrthopaedic SurgeryOrthopedic SurgeryAllergyHypersensitivityOrthopaedic BiomaterialsAllergen ExposureAllergic Skin DiseasesContact AllergyContact DermatitisPatch TestingSkin Prick TestingChromium Allergy TestingCobalt Allergic Contact DermatitisCobalt Allergy TestingIntracutaneous ReactivityMetal Allergy TestingMetal HypersensitivityOrthopaedic ComplicationsOrthopaedic Implants
Patients with a contact allergy to chromium, cobalt and/or nickel, patch test verified before implantation of a metallic orthopaedic device, were followed up years later by clinical and radiographic examination as well as with epicutaneous and intracutaneous tests. Eighteen patients had been exposed to an orthopaedic implant for several years (mean 6.3 years) containing a metal to which they were allergic. None had suffered any dermatologic or orthopaedic complications attributable to the contact allergy.