DergiPark (Istanbul University) · 2006 · 72 citations · 1 references
Open access
MedicineMedicinal ChemistryPharmacologyChemotherapyDrug DiscoveryStructure-activity RelationshipsAntibacterial PharmacologyAntifungal AgentsAntifungal PharmacologyAntifungal TherapyAntifungal ChemotherapyBenzimidazole ChemistryBenzimidazole SynthesisNatural Antifungal CompoundsNew Antifungal AgentsNovel Antifungal Drug Development
Some benzimidazole derivatives were synthesized and their in vitro antifungal activities were tested against Candida albicans, Candida glabrata and Candida krusei. Compounds 6 and 9 possessed activity comparable to fluconazole against C. albicans with a minimum inhibitory concentration of 12.5 m g/mL.
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