Simple and sensitive determination of 5-fluorouracil in plasma by high-performance liquid chromatography

Pharmacokinetics of 5-fluorouracil administered orally, by rapid intravenous and by slow infusion.

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Pharmaceutical Science, Pharmacokinetic Modeling, Pharmacological Study +9

Relationship between 5-fluorouracil (5-FU) dose intensity and therapeutic response in patients with advanced colorectal cancer receiving infusional therapy containing 5-FU

Érick Gamelin, E Danquechin‐Dorval, Y. Dumesnil et al. · Cancer · 1996 · 211 citations · Full text

5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer

J. Santini, G. Milano, Antoine Thyss et al. · British Journal of Cancer · 1989 · 173 citations · Full text

Dose Adjustment, Radiation Therapy, Medicine +10

Relationship between fluorouracil systemic exposure and tumor response and patient survival.

G. Milano, M C Etienne, N. Renée et al. · Journal of Clinical Oncology · 1994 · 160 citations

Long-term weekly treatment of colorectal metastatic cancer with fluorouracil and leucovorin: results of a multicentric prospective trial of fluorouracil dosage optimization by pharmacokinetic monitoring in 152 patients.

Érick Gamelin, M. Boisdron‐Celle, R. Delva et al. · Journal of Clinical Oncology · 1998 · 158 citations