Concepedia

Irbesartan, an FDA approved drug for hypertension and diabetic nephropathy, is a potent inhibitor for hepatitis B virus entry by disturbing Na+-dependent taurocholate cotransporting polypeptide activity

Xuejun Wang, Wei Hu, Tingyu Zhang, Yingying Mao, Nannan Liu, Shengqi Wang

Antiviral Research · 2015 · 61 citations · 32 references

DOI

Concepts

References

32

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

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Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes

Edmund J. Lewis, Lawrence G. Hunsicker, William R. Clarke et al. · New England Journal of Medicine · 2001 · 6K citations · Full text

, , +16

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

F. Ann Ran, Patrick D. Hsu, Chie-Yu Lin et al. · Cell · 2013 · 3.4K citations · Full text

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Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

Huan Yan, Guocai Zhong, Guangwei Xu et al. · eLife · 2012 · 2.1K citations · Full text

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Infection of a human hepatoma cell line by hepatitis B virus

Philippe Gripon, Sylvie Rumin, Stephan Urban et al. · Proceedings of the National Academy of Sciences · 2002 · 1.2K citations · Full text

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