X-chromosome inactivation and the Xg locus.

A familial disorder of uric acid metabolism and central nervous system function

Michael Lesch, William L. Nyhan · The American Journal of Medicine · 1964 · 1.5K citations

Clinical Disorders, Urological Research, Uric Acid Metabolism +9

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

J. Edwin Seegmiller, Frederick M. Rosenbloom, William N. Kelley · Science · 1967 · 1.2K citations

Sexual Disorders, Enzyme Defect Associated, Adrenal Gland +18

Clonal origin of chronic myelocytic leukemia in man.

PJ Fialkow, Stanley M. Gartler, Akira Yoshida · Proceedings of the National Academy of Sciences · 1967 · 528 citations · Full text

The Distribution of the Philadelphia Chromosome in Patients with Chronic Myelogenous Leukemia

JACQUELINE WHANG, Emil Frei, J. H. Tjio et al. · Blood · 1963 · 295 citations · Full text

Hemizygous Expression of Glucose-6-Phosphate Dehydrogenase in Erythrocytes of Heterozygotes for the Lesch-Nyhan Syndrome

William L. Nyhan, Bohdan Bakay, James D. Connor et al. · Proceedings of the National Academy of Sciences · 1970 · 209 citations · Full text

Cytogenetics, Genetics, Pathology +21