Concepedia

Clinical islet transplantation in type 1 diabetes mellitus: results of Australia's first trial

Philip J. O’Connell, Wayne J. Hawthorne, Brian J. Nankivell, Anita T. Patel, Stacey N. Walters, Henry Pleass, Richard D. Allen, Jeremy R. Chapman, D. Jane Holmes–Walker, Jenny E. Gunton

The Medical Journal of Australia · 2006 · 75 citations · 16 references

DOI

Abstract

Islet transplantation is effective at improving glycaemic control and hypoglycaemia unawareness in the short to medium term. However, problems with long-term safety of immunosuppression, islet-induced thrombosis and early detection of loss of islet function remain to be addressed.

References

16

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

A.M. James Shapiro, Jonathan R.T. Lakey, Edmond A. Ryan et al. · New England Journal of Medicine · 2000 · 5.2K citations · Full text

Five-Year Follow-Up After Clinical Islet Transplantation

Edmond A. Ryan, Breay W. Paty, Peter Senior et al. · Diabetes · 2005 · 1.6K citations · Full text

Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol

Edmond A. Ryan, Jonathan R. T. Lakey, Ray V. Rajotte et al. · Diabetes · 2001 · 868 citations · Full text

Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy

William B. Kelly, Richard C. Lillehei, Frank Merkel et al. · Transplantation · 1968 · 726 citations

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Islet isolation assessment in man and large animals

Camillo Ricordi, Derek W. R. Gray, Bernhard J. Hering et al. · Acta Diabetologica · 1990 · 576 citations

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