Dynorphin activation of kappa opioid receptor reduces neuronal excitability in the paraventricular nucleus of mouse thalamus

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

G. Di Chiara, Assunta Impérato · Proceedings of the National Academy of Sciences · 1988 · 4.7K citations · Full text

Medicine, Neuroscience, Pharmacology +17

Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

Laura Bohn, Robert J. Lefkowitz, Raul R. Gainetdinov et al. · Science · 1999 · 1.1K citations

Medicine, Pharmacology, Cell Signaling +16

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Laura Bohn, Raul R. Gainetdinov, Fang‐Tsyr Lin et al. · Nature · 2000 · 916 citations

Medicine, Neuroscience, Pharmacology +14

Psychotomimesis Mediated by κ Opiate Receptors

Andreas Pfeiffer, Victor Brantl, Albert Herz et al. · Science · 1986 · 858 citations

Medicine, Behavioral Sciences, Pharmacology +16

Organization of the afferent connections of the mediodorsal thalamic nucleus in the rat, related to the mediodorsal-prefrontal topography

Henk J. Groenewegen · Neuroscience · 1988 · 730 citations

Life Sciences, Neurobiology, Neuroscience +13