Enhanced Delivery of Zidovudine Through Rat and Human Skin via Ester Prodrugs

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

Hiroaki Mitsuya, Kent J. Weinhold, P A Furman et al. · Proceedings of the National Academy of Sciences · 1985 · 1.9K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Plasma and cerebrospinal fluid pharmacokinetics of 3′-azido-3′-deoxythymidine: A Novel pyrimidine analog with potential application for the treatment of patients with AIDS and related diseases

Raymond W. Klecker, Jerry M. Collins, Robert Yarchoan et al. · Clinical Pharmacology & Therapeutics · 1987 · 381 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +11

EFFECTS OF ZIDOVUDINE IN 365 CONSECUTIVE PATIENTS WITH AIDS OR AIDS-RELATED COMPLEX

E Dournon, Willy Rozenbaum, Christophe Michon et al. · The Lancet · 1988 · 180 citations

Medicine, Infectious Diseases, Pharmacology +9

The effects of ethanol on the transport of β-estradiol and other permeants in hairless mouse skin. II. A new quantitative approach

Abdel‐Halim Ghanem, Hanaa Mahmoud, William l. Higuchi et al. · Journal of Controlled Release · 1987 · 127 citations

Life Sciences, Endocrinology, Toxicology +15

Effect and mode of action of aliphatic esters on the in vitro skin permeation of nicorandil

Kiyoshi Sato, Kenji Sugibayashi, Yasunori Morimoto · International Journal of Pharmaceutics · 1988 · 115 citations

Pharmacy, Pharmaceutics, Pharmacology +14