Concepedia

Prognostic significance of nuclear and cytoplasmic expression of metallothioneins as related to proliferative activity in squamous cell carcinomas of oral cavity.

Jolanta Szelachowska, Piotr Dzięgiel, Joanna Jeleń-Krzeszewska, Michał Jeleń, Radosław Tarkowski, Iwona Włodarska, Barbara Spytkowska, Iwona Gisterek, Rafał Matkowski, Jan Kornafel

PubMed · 2008 · 30 citations · 33 references

DOI

Abstract

This is relevant evidence that MT overexpression could be related to worse prognosis in patients with oral cancer. We have found no relationship between MT expression and proliferative activity.

References

33

Recurrence at the primary site in head and neck cancer and the significance of neck lymph node metastases as a prognostic factor

C. René Leemans, Rammohan Tiwari, Jos J. P. Nauta et al. · Cancer · 1994 · 419 citations

Resistance against cis-dichlorodiammineplatinum in cultured cells with a high content of metallothionein

Arne Bakka, Liv Endresen, Alf B.S. Johnsen et al. · Toxicology and Applied Pharmacology · 1981 · 168 citations

, , +7

Nuclear localization of metallothionein during cell proliferation and differentiation.

M.George Cherian, Margarita D. Apostolova · PubMed · 2000 · 164 citations

, , +14

Cell cycle regulation of metallothionein in human colonic cancer cells.

W. Nagel, Bert L. Vallée · Proceedings of the National Academy of Sciences · 1995 · 152 citations · Full text

, , +14

T1 and T2 squamous cell carcinoma of the oral tongue: Prognostic factors and the role of elective lymph node dissection

Samuel W. Beenken, Helen Krontiras, William A. Maddox et al. · Head & Neck · 1999 · 132 citations