Analysis of DNA polymorphisms suggests that most de novo dup(21q) chromosomes in patients with Down syndrome are isochromosomes and not translocations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

Randall K. Saiki, Stephen J. Scharf, Fred Faloona et al. · Science · 1985 · 9K citations

Medicine, Genetics, Molecular Genetics +17

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

J L Weber, Paula E. May · PubMed · 1989 · 3.4K citations

Life Sciences, Genetics, Molecular Genetics +14

Hypervariability of simple sequences as a general source for polymorphic DNA markers

Diethard Tautz · Nucleic Acids Research · 1989 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +7

A hypervariable microsatellite revealed by in vitro amplification of a dinucleotide repeat within the cardiac muscle actin gene.

M. Litt, J.A. Luty · PubMed · 1989 · 2K citations

Life Sciences, Genetics, Molecular Genetics +7

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

Louis M. Kunkel, Kirby D. Smith, Samuel H. Boyer et al. · Proceedings of the National Academy of Sciences · 1977 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +15