Size, shape, and orientation of neurons in the left and right hippocampus: investigation of normal asymmetries and alterations in schizophrenia

Abstract

The data confirm that hippocampal neuronal size is decreased in schizophrenia and reveal that the shape of neurons is altered, supporting the view that hippocampal cytoarchitectural abnormalities may be part of the cerebral substrate of schizophrenia. They also provide further evidence that the abnormalities are localized and lateralized.