A cross-sectional study of parkinsonism and tardive dyskinesia in lithium-treated affective disordered patients.

Abstract

The combination of lithium and neuroleptics was associated with a high prevalence of EPS. The presence of TD in lithium-treated patients not treated with neuroleptics for at least 6 months is consistent with the hypothesis that lithium may exacerbate the vulnerability of affective disordered patients to dyskinesias.