PubMed · 2012 · 84 citations · 137 references
Open access
Life SciencesCell BiologyHematologyCell TherapyRegenerative MedicineStem Cell BiologyCell-based TherapiesCellular TherapyEmbryonic Stem CellsAdult Stem Cell TherapiesStem Cell-based Therapy
Stem cells are undifferentiated cells with the ability of proliferation, regeneration, conversion to differentiated cells and producing various tissues. Stem cells are divided into two categories of embryonic and adult. In another categorization stem cells are divided to Totipotent, Multipotent and Unipotent cells.So far usage of stem cells in treatment of various blood diseases has been studied (such as lymphoblastic leukemia, myeloid leukemia, thalassemia, multiple myeloma and cycle cell anemia). In this paper the goal is evaluation of cell therapy in treatment of Parkinson's disease, Amyotrophic lateral sclerosis, Alzheimer, Stroke, Spinal Cord Injury, Multiple Sclerosis, Radiation Induced Intestinal Injury, Inflammatory Bowel Disease, Liver Disease, Duchenne Muscular Dystrophy, Diabetes, Heart Disease, Bone Disease, Renal Disease, Chronic Wounds, Graft-Versus-Host Disease, Sepsis and Respiratory diseases. It should be mentioned that some disease that are the target of cell therapy are discussed in this article.
137
Embryonic Stem Cell Lines Derived from Human Blastocysts
James A. Thomson, Joseph Itskovitz‐Eldor, Sander S. Shapiro et al. · Science · 1998 · 15.9K citations
Sarah H. Wild, Gojka Roglić, Anders Green et al. · Diabetes Care · 2004 · 15.3K citations
Establishment in culture of pluripotential cells from mouse embryos
Martin Evans, M. H. Kaufman · Nature · 1981 · 8.6K citations
RETRACTED ARTICLE: Pluripotency of mesenchymal stem cells derived from adult marrow
Yuehua Jiang, Balkrishna Jahagirdar, R. Lee Reinhardt et al. · Nature · 2002 · 5.5K citations