Monocyte and microglial activation in patients with mood-stabilized bipolar disorder

Joel Jakobsson, Maria Bjerke, Sara Sahebi, Anniella Isgren, Carl Johan Ekman, Carl M. Sellgren, Bob Olsson, Henrik Zetterberg, Kaj Blennow, Erik Pålsson,

Journal of Psychiatry and Neuroscience · 2015 · 101 citations · 35 references

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Abstract

Our results suggest that both neuroinflammatory and systemic inflammatory processes are involved in the pathophysiology of bipolar disorder. Importantly, markers of immunological processes in the brain were independent of peripheral immunological activity.

References

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