[Mucin accumulation in the dermis and REM syndrome].

Abstract

Mucus, glucosaminoglycans, and proteoglycans, are produced by fibroblasts. Qualitative and quantitative differences in the dermal mucus are to be seen in mucinoses, partly due to factors in the blood serum. A survey of patients with REM-syndrome--our own patients and those described in other studies--is given, together with cases of the plaque-like form of cutaneous mucinosis. Both conditions are closely related but, in our opinion, not identical. Our findings suggest that the mucous compounds are eliminated from the tissue by the blood vessels and the lymphatics. As a result an increase of mucin may be found in the blood serum.