Concepedia

Comparison of the Effects of Glibenclamide on Metabolic Parameters, GLUT1 Expression, and Liver Injury in Rats With Severe and Mild Streptozotocin-Induced Diabetes Mellitus

Jeļizaveta Sokolovska, Sergejs Isajevs, Olga Sugoka, Jelena Sharipova, Natalia Paramonova, Darja Isajeva, Evita Rostoka, Tatjana Sjakste, Ivars Kalvinsh, Nikolajs Sjakste

Medicina · 2012 · 29 citations · 19 references

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Abstract

The GLUT1 expression was found to be affected by the glucose and insulin levels and can be modulated by glibenclamide in severely and mildly diabetic rats. Glibenclamide can prevent the liver damage caused by severe hyperglycemia.

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