Concepedia

S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis.

Ahmed M. Abu El‐Asrar, Mohd Imtiaz Nawaz, Gert De Hertogh, Kaiser Alam, Mohammad Mairaj Siddiquei, Kathleen Van den Eynde, Ahmed Mousa, Ghulam Mohammad, Karel Geboes, Ghislain Opdenakker

PubMed · 2014 · 47 citations · 53 references

Abstract

S100A4 represents a valuable vitreous marker molecule in the pathogenesis of PDR and might become a new target for the treatment of PDR.

References

53

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

Lloyd Paul Aiello, Robert L. Avery, Paul G. Arrigg et al. · New England Journal of Medicine · 1994 · 3.8K citations · Full text

A central role for inflammation in the pathogenesis of diabetic retinopathy

Antonia M. Joussen, Vassiliki Poulaki, Minh Ly Le et al. · The FASEB Journal · 2004 · 1.2K citations

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Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

Elisabeth M. Zeisberg, Scott Potenta, Hikaru Sugimoto et al. · Journal of the American Society of Nephrology · 2008 · 849 citations · Full text

Up-Regulation and Profibrotic Role of Osteopontin in Human Idiopathic Pulmonary Fibrosis

Annie Pardo, Kevin F. Gibson, José Cisneros et al. · PLoS Medicine · 2005 · 490 citations · Full text

Osteopontin, a Novel Substrate for Matrix Metalloproteinase-3 (Stromelysin-1) and Matrix Metalloproteinase-7 (Matrilysin)

Renu Agnihotri, Howard C. Crawford, Hirotaka Haro et al. · Journal of Biological Chemistry · 2001 · 420 citations · Full text