Emergence of extensive drug resistance (XDR) among Gram-negative bacilli in South Africa looms nearer.

Adrian Brink, Charles Feldman, Guy A. Richards, Johan Moolman, Marthinus Senekal

PubMed · 2008 · 36 citations · 0 references

Concepts

Abstract

Until recently, the term 'extensive drug resistance' (XDR) was held to be applicable to Mycobacterium tuberculosis only. It is now clear that Gram-negative bacilli are moving a step closer towards acquiring similar resistance. The emergence of multi- (MDR) and pan-drug resistant (PDR) Gram-negative health care-associated pathogens has been confined to non-fermenters such as Pseudomonas aeruginosa and Acinetobacter baumannii.