Concepedia

Ciliotherapy: a novel intervention in polycystic kidney disease.

Sarmed H. Kathem, Ashraf M. Mohieldin, Shakila Abdul-Majeed, Sajida H Ismail, Qaiss H Altaei, Ibrahim K Alshimmari, Mohanned M Alsaidi, Hussein Khammas, Andromeda M. Nauli, Bina Joe,

PubMed · 2014 · 30 citations · 18 references

DOIFull text

Open access

Abstract

Overall, our studies provide the first evidence of ciliotherapy as an innovative intervention in patients with abnormal primary cilia.

References

18

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Surya M. Nauli, Francis J. Alenghat, Ying Luo et al. · Nature Genetics · 2003 · 2K citations

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Unified Criteria for Ultrasonographic Diagnosis of ADPKD

York Pei, James Obaji, Annie Dupuis et al. · Journal of the American Society of Nephrology · 2008 · 734 citations · Full text

Evaluation of ultrasonographic diagnostic criteria for autosomal dominant polycystic kidney disease 1

David Ravine, LJ Sheffield, D. M. Danks et al. · The Lancet · 1994 · 562 citations

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Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1

Surya M. Nauli, Yoshifumi Kawanabe, John J. Kaminski et al. · Circulation · 2008 · 452 citations · Full text

Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades

Wissam A. AbouAlaiwi, Maki Takahashi, Blair Mell et al. · Circulation Research · 2009 · 326 citations · Full text