Phagocytic activity of human blood platelets examined by electron microscopy.

Abstract

On the basis of a previously elaborated system for testing the phagocytic ability of the human blood platelets we have undertaken studies of testing the interaction between platelet and bacteria during phagocytosis examined by the electron microscope. We have found that during phagocytosis platelets lose their discoid shape and demonstrate numerous pseudopods. During 2 min a complete engulfment of the bacterium could be observed. 10 min after starting phagocytosis it is possible to note partially destroyed bacteria. The role of human blood platelets in the antibacterial mechanisms is briefly discussed.