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Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling

Isabelle F. Foote, Jonny P Flint, Anna E. Fürtjes, Jeremy M Lawrence, Donncha S. Mullin, John D. Fisk, Tobias K. Karakach, Andrew D. Rutenberg, Nicholas G. Martin, Michelle K. Lupton,

Nature Genetics · 2025 · 14 citations · 74 references

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74

Frailty in Older Adults: Evidence for a Phenotype

Linda P. Fried, Catherine M. Tangen, Jeremy Walston et al. · The Journals of Gerontology Series A · 2001 · 24.5K citations · Full text

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Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Yingyao Zhou, Bin Zhou, Lars Pache et al. · Nature Communications · 2019 · 15.6K citations · Full text

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The Application of Electronic Computers to Factor Analysis

Henry F. Kaiser · Educational and Psychological Measurement · 1960 · 12.2K citations

, , +9

The mutational constraint spectrum quantified from variation in 141,456 humans

Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao et al. · Nature · 2020 · 10.1K citations · Full text

, , +17

Integrative analysis of 111 reference human epigenomes

Anshul Kundaje, Wouter Meuleman, Jason Ernst et al. · Nature · 2015 · 7.1K citations · Full text

, , +16