Multi-cohort validation of a lipid metabolism and ferroptosis-associated index for prognosis and immunotherapy response prediction in hormone receptor-positive breast cancer

Cheng Zeng, Jiani Wang, Shen Zhao, Yuhan Wei, Yalong Qi, Shuning Liu, Yuanyi Wang, Hewei Ge, Xiaoqi Yang, Yujing Tan,

International Journal of Biological Sciences · 2025 · 13 citations · 0 references

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Abstract

This study identified distinct LMF-related molecular clusters in HR+ breast cancer with unique prognostic and immune characteristics. The LMF_index shows potential as a prognostic biomarker and a guide for immunotherapy strategies in HR+ breast cancer.