Concepedia

Renal tubular epithelial IGFBP7 interacts with PKM2 to drive renal lipid accumulation and fibrosis

Ju-tao Yu, Shuai-shuai Xie, Xiaoyu Shen, Li Zeng, Xiaowei Hu, Yao Zhang, Ze-hui Dong, Xiangyu Li, Yuhang Dong, Chao Li,

Molecular Therapy · 2025 · 13 citations · 42 references

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References

42

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

Chunaram Choudhary, Chanchal Kumar, Florian Gnad et al. · Science · 2009 · 4K citations · Full text

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Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

Weiwei Yang, Yan Xia, Haitao Ji et al. · Nature · 2011 · 1K citations · Full text

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PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

Weiwei Yang, Yan Xia, David H. Hawke et al. · Cell · 2012 · 847 citations · Full text

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Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCFFbw7

Anders Sundqvist, Maria T. Bengoechea-Alonso, Xin Ye et al. · Cell Metabolism · 2005 · 449 citations · Full text

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Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker

Wenjun Ju, Viji Nair, Shahaan Smith et al. · Science Translational Medicine · 2015 · 430 citations

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