Concepedia

Structural insights and <i>in vitro</i> and <i>in vivo</i> anticancer evaluation of dithiocarbamate-based metal complexes against murine lymphoma

Anupam Singh, Riya Patel, Samrat Daripa, M.K. Bharty, Ray J. Butcher, Sumit Kumar Hira, Lal Bahadur Prasad

Dalton Transactions · 2025 · 10 citations · 31 references

DOI

Concepts

Abstract

The promising in vitro and in vivo efficacy, combined with favorable biosafety, positions zinc( ii ) N -cyclohexyl N -(4-methylbenzyl) dithiocarbamate complexes as potential candidates for anti-lymphoma therapies.

References

31

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Hyuna Sung, Jacques Ferlay, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2021 · 112.5K citations · Full text

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Cancer statistics, 2016

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The importance of sulfur-containing motifs in drug design and discovery

Muhamad Mustafa, Jean‐Yves Winum · Expert Opinion on Drug Discovery · 2022 · 218 citations

, , +16

Ni(II), Cu(II), and Zn(II) Diethyldithiocarbamate Complexes Show Various Activities Against the Proteasome in Breast Cancer Cells

Boris Cvek, Vesna Milacic, Jan Taraba et al. · Journal of Medicinal Chemistry · 2008 · 208 citations · Full text

, , +12

DNA Binding, Cleavage, and Cytotoxic Activity of the Preorganized Dinuclear Zinc(II) Complex of Triazacyclononane Derivatives

Xin Sheng, Xun Guo, Xiaomin Lu et al. · Bioconjugate Chemistry · 2008 · 122 citations

, , +16