Concepedia

Lactylation-driven USP4-mediated ANXA2 stabilization and activation promotes maintenance and radioresistance of glioblastoma stem cells

Yiming Tu, Lei Xu, Guoqiang Fu, Jichen Wang, Pengfei Xia, Zeqiang Tao, Yangfan Ye, Jingming Hu, Wanzhi Cai, Hang Zhu,

Cell Death and Differentiation · 2025 · 24 citations · 50 references

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Roger Stupp, Monika E. Hegi, Warren Mason et al. · The Lancet Oncology · 2009 · 7.8K citations

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Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Roel G.W. Verhaak, Katherine A. Hoadley, Elizabeth Purdom et al. · Cancer Cell · 2010 · 7.7K citations · Full text

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Immunotherapy of Diffuse Gliomas: Biological Background, Current Status and Future Developments

Brain Pathology · 2009 · 4K citations · Full text

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Metabolic regulation of gene expression by histone lactylation

Di Zhang, Zhanyun Tang, He Huang et al. · Nature · 2019 · 3.9K citations · Full text

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Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment

Qianghu Wang, Baoli Hu, Xin Hu et al. · Cancer Cell · 2017 · 2.1K citations · Full text

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