Lactate-triggered histone lactylation contributes to podocyte epithelial-mesenchymal transition in diabetic nephropathy in mice

Metabolic regulation of gene expression by histone lactylation

Di Zhang, Zhanyun Tang, He Huang et al. · Nature · 2019 · 3.5K citations · Full text

Histone Modifications, Chromatin, Chromatin Remodeling +7

TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation

Ricardo A. Irizarry-Caro, Margaret M. McDaniel, Garrett R. Overcast et al. · Proceedings of the National Academy of Sciences · 2020 · 417 citations · Full text

Epithelial-to-Mesenchymal Transition Is a Potential Pathway Leading to Podocyte Dysfunction and Proteinuria

Yingjian Li, Young Sun Kang, Chunsun Dai et al. · American Journal Of Pathology · 2008 · 336 citations · Full text

Epithelial-to-mesenchymal Transition, Urology, Renal Function +12

Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction

Min Fan, Kun Yang, Xiaohui Wang et al. · Science Advances · 2023 · 322 citations · Full text

Lung Myofibroblasts Promote Macrophage Profibrotic Activity through Lactate-induced Histone Lactylation

Huachun Cui, Na Xie, Sami Banerjee et al. · American Journal of Respiratory Cell and Molecular Biology · 2020 · 315 citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Immunology +19