Design of Highly Adhesive Urchin‐Like Gold Nanostructures for Effective Topical Drug Administration and Symptomatic Relief of Corneal Dryness

Abstract

Bioadhesive Nanodrug Administrators The cover image illustrates the effect of eye drops based on gold nanourchins for the comprehensive relief of dry eye syndrome. In article number 2400484, Jui-Yang Lai and co-workers show that these rough nanostructures show extended ocular retention, resulting in high bioavailability of grafted quercetin, thus allowing for single-dose administration to substantially increase tear production and restore ocular surface integrity, surpassing the efficacy of conventional drugs.