Antinociceptive Effects of δ-Opioid Agonists in Rhesus Monkeys: Effects on Chemically Induced Thermal Hypersensitivity

Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors.

Christoph Stein, M J Millan, Toni S. Shippenberg et al. · Journal of Pharmacology and Experimental Therapeutics · 1989 · 528 citations

Medicine, Pharmacology, Inflammation +16

Mediation of primary afferent peripheral hyperalgesia by the cAMP second messenger system

Yetunde O. Taiwo, L.K. Bjerknes, Edward J. Goetzl et al. · Neuroscience · 1989 · 240 citations

Life Sciences, Neuroscience, Pharmacology +14

Probes for Narcotic Receptor Mediated Phenomena. 19. Synthesis of (+)-4-[(.alpha.R)-.alpha.-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC 80): A Highly Selective, Nonpeptide .delta. Opioid Receptor Agonist

Silvia N. Calderon, Richard B. Rothman, Frank Porreca et al. · Journal of Medicinal Chemistry · 1994 · 217 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

SNC 80, a selective, nonpeptidic and systemically active opioid delta agonist.

Edward J. Bilsky, Silvia N. Calderon, T Wang et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 199 citations

Medicine, Neurobiology, Pharmacology +16

Hyperalgesia and allodynia

APS Journal · 1992 · 180 citations