ESMO Clinical Practice Guideline interim update on the management of biliary tract cancer

Abstract

• This ESMO Clinical Practice Guideline update addresses new developments in the management of biliary tract cancer. • Recommendations are given for first-line treatment with immune checkpoint inhibitors. • Key recommendations are also provided for second-line treatment with targeted therapies. • The update also covers the latest developments in molecular testing and intra-arterial therapies. • A management algorithm for early-stage, locally advanced and advanced/metastatic disease is provided.