Flexible paper-based Ag dendritic SERS chips for rapid <i>in situ</i> detection of thiram residues on pear skin

Abstract

M. The chip substrate also exhibits outstanding reliability, with reproducibility and repeatability both less than 5%. Furthermore, the flexible nature of the paper substrate enables it to conform to curved surfaces and be in direct contact with analytes, exemplified by its ability to adhere to and retrieve thiram from pear skin using a novel "paste-and-peel-off" technique. The substrate shows remarkable performance for thiram detection on pear skin, with sharp recovery rates ranging from 90% to 105%. With its facile fabrication, excellent sensitivity, high reliability, and practical applicability in non-invasive sampling, the paper-based Ag dendritic SERS substrate offers significant potential as an advanced substrate to bring SERS out of the laboratory and closer to real-world applications.