Concepedia

A doxorubicin loaded chitosan–poloxamer <i>in situ</i> implant for the treatment of breast cancer

Deepak Pradhan, Jitu Halder, Tushar Kanti Rajwar, Ritu Mahanty, Ivy Saha, Ajit Mishra, Priyanka Dash, Chandan Dash, Jameel Al‐Tamimi, Salim Manoharadas,

RSC Advances · 2024 · 22 citations · 28 references

DOIFull text

Open access

Concepts

Abstract

Doxorubicin-containing in situ gel made with chitosan (0.5% w/v) and poloxamer 407 (20% w/v) had a better biological and pharmacokinetic profile than the pure drug.

References

28

A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery

Taís Gratieri, Guilherme M. Gelfuso, Eduardo Melani Rocha et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2010 · 372 citations

, , +14

Enzymic preparation of water-soluble chitosan and their antitumor activity

Caiqin Qin, Yumin Du, Ling Xiao et al. · International Journal of Biological Macromolecules · 2002 · 306 citations

, , +7

Metronomic Chemotherapy: Changing the Paradigm That More Is Better

O. Graciela Scharovsky, L. E. Mainetti, V. R. Rozados · Current Oncology · 2009 · 175 citations · Full text

, , +11

Fabrication of biodegradable gelatin/chitosan/cinnamaldehyde crosslinked membranes for antibacterial wound dressing applications

El‐Refaie Kenawy, Ahmed M. Omer, Tamer M. Tamer et al. · International Journal of Biological Macromolecules · 2019 · 170 citations

, , +14

Chitosan drives anti-inflammatory macrophage polarisation and pro-inflammatory dendritic cell stimulation

M I Oliveira, MJ Oliveira, A.L. Torres et al. · European Cells and Materials · 2012 · 169 citations · Full text

, , +17